The Nirenberg and Matthaei experiment was performed by American biologist Marshall W. Nirenberg (1927-2010) and German biologist J. Heinrich Matthaei in 1961. Matthaeiat was a postdoc fellow in the lab of Nirenberg at the National Institutes of Health, USA. The Nirenberg […]
The genome of E coli contains 4 million base pairs or 4×106 bp. The number of turns of DNA present is 400,000 turns or (4×105) turns. In general, in the B form of DNA, one […]
Histones are basic proteins that in association with DNA form a structure known as the nucleosome. Nucleosomes help in the condensation of DNA into chromatin inside the eukaryotic nucleus. The nucleosome consists of four types […]
The bioinformatics tool that is not used to analyze the restriction enzymes sites of a DNA sequence is EuGene. NEBcutter, Webcutter, and WatCut are the bioinformatics online tools used for analyzing and predicting the cutting […]
Erwin Chargaff proposed a rule called the Chargaff’s rules which states that in a double-stranded DNA segment, the ratio of purine bases (Adenine+Guanine) and the pyrimidine bases (Cytosine+Thymine) is equal to 1.0 and the number of […]
DNA is tightly packed in the form of condensed chromatin structure to form chromosomes. The nucleosome is the unit of chromatin that form from eight core histone (2 units of each H2A, H2B, H3, and […]
After transcription, a cap forms at the 5′ end of the mRNA in eukaryotes. The cap forms by the attachment of 7-methyl guanosine (m7G). 7-methyl guanosine is a modified guanosine nucleotide where a methyl (-CH3) […]
B-DNA is the right-handed DNA helix that is the original model of DNA proposed by JD Watson and F Crick. In the B-DNA model, two DNA strands twist around each other spirally in a right-handed […]
The gene of a Eukaryotic organism contains two kinds of base sequences. These sequences are known as Intron or intragenic region and Exon. The intron is a part of a gene that is removed during […]
The double helix structure is formed by two strands of nucleic acids such as DNA. The two strands are joined together by hydrogen bonds between the nucleotides (A-T and G-C) of two strands that run […]
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