The number of sex chromosomes is normal for Down’s syndrome. Down syndrome is a genetic disorder and caused due to abnormal cell division that results in an extra copy of chromosome 21 (trisomy 21). A […]
The Philadelphia chromosome is a genetic abnormality found on chromosome 22 of chronic myeloid leukemia (CML) patients. The abnormality arises due to the reciprocal translocation between chromosome 22 and chromosome 9 (t(9;22)(q34;q11)) and a fused gene called BCR-ABL1. The translocation is also known as the Philadelphia […]
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