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Polish biologist “Rudolf Stefan Jan Weigl” known for the development of the Typhus vaccine. Epidemic typhus or louse-borne typhus is a disease caused by the bacterium Rickettsia prowazekii. Rickettsia prowazekii is a gram-negative, rod-shaped, aerobic bacteria. The pathogen is transmitted by the human body louse ( Pediculus humanus corporis ). The fatality rate of untreated typhus cases is approximately 40%. The main reservoir for the bacterium R. prowazekii is the flying squirrel in North America. The sign and symptoms of Typhus include fever, headache, falling blood pressure, body and muscle aches, cough, nausea, and vomiting.
Rudolf Stefan Jan Weigl (2 September 1883 – 11 August 1957), was continuously nominated for the Nobel Prize in Physiology and Medicine each year between 1930 and 1939 for the development of the Typhus vaccine but did not receive the prize.