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The structure of a nucleosome consists of a segment of DNA (146 bp) wound around eight histone proteins ( 2 copies each of H2A, H2B, H3 and H4). In eukaryotes, the nucleosome is the basic structural unit of DNA packaging in the nucleus. Under an electron microscope, the non-condensed nucleosomes without the linker histone resemble "beads on a string of DNA".
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